Chromatin remodeler ARID1A binds IRF3 to selectively induce antiviral interferon production in macrophages

Chromatin remodeler ARID1A binds IRF3 to selectively induce antiviral interferon production in macrophages

Abstract Transcription factor IRF3 is critical for the induction of antiviral type I interferon (IFN-I). The epigenetic regulation of IFN-I production in antiviral innate immunity needs to be further identified. Here, we reported that epigenetic remodeler ARID1A, a critical component of the mSWI/SNF...

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Bibliographic Details
Main Authors: Ye Hu, Xin Wang, Jiaying Song, Jiacheng Wu, Jia Xu, Yangyang Chai, Yuanyuan Ding, Bingjing Wang, Chunmei Wang, Yong Zhao, Zhongyang Shen, Xiaoqing Xu, Xuetao Cao
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04032-9

Internet

https://doi.org/10.1038/s41419-021-04032-9

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