Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells

Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells

Mammalian pluripotent stem cells (PSCs) represent an important venue for understanding basic principles regulating tissue-specific differentiation and discovering new tools that may facilitate clinical applications. Mechanisms that direct neural differentiation of PSCs involve growth factor signalin...

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Bibliographic Details
Main Authors: Yaping Sun, Zhiqiang Dong, Taihao Jin, Kean-Hooi Ang, Miller Huang, Kelly M Haston, Jisong Peng, Tao P Zhong, Steven Finkbeiner, William A Weiss, Michelle R Arkin, Lily Y Jan, Su Guo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-09-01
Series:eLife
Subjects:
chemical genetic
small molecule tool
cellular differentiation
dopaminergic neuron
pluripotent stem cell
Online Access:https://elifesciences.org/articles/00508

Internet

https://elifesciences.org/articles/00508

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