Tuberatolide B isolated from Sargassum macrocarpum inhibited LPS-stimulated inflammatory response via MAPKs and NF-κB signaling pathway in RAW264.7 cells and zebrafish model

Tuberatolide B isolated from Sargassum macrocarpum inhibited LPS-stimulated inflammatory response via MAPKs and NF-κB signaling pathway in RAW264.7 cells and zebrafish model

Brown algae are known to contain rich anti-inflammatory compounds. The objective of this study was to identify anti-inflammatory compound in the Sargassum macrocarpum and anti-inflammatory effect of tuberatolide B (TTB) was investigated. TTB significantly suppressed the production of NO and pro-infl...

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Bibliographic Details
Main Authors: Eun-A Kim, Seo-Young Kim, Junseong Kim, Jae-Young Oh, Hyun-Soo Kim, Weon-Jong Yoon, Do-Hyung Kang, Soo-Jin Heo
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Journal of Functional Foods
Subjects:
Sargassum macrocarpum
Tuberatolide B
Anti-inflammatory
RAW264.7 cells
Zebrafish
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618305516

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http://www.sciencedirect.com/science/article/pii/S1756464618305516

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