GRIP1 Binds to ApoER2 and EphrinB2 to Induce Activity-Dependent AMPA Receptor Insertion at the Synapse

GRIP1 Binds to ApoER2 and EphrinB2 to Induce Activity-Dependent AMPA Receptor Insertion at the Synapse

Regulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking in response to neuronal activity is critical for synaptic function and plasticity. Here, we show that neuronal activity induces the binding of ephrinB2 and ApoER2 receptors at the postsynapse to regulate d...

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Bibliographic Details
Main Authors: Sylvia Pfennig, Franziska Foss, Diane Bissen, Eva Harde, Julia C. Treeck, Marta Segarra, Amparo Acker-Palmer
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Cell Reports
Subjects:
GRIP1
AMPA receptors
synaptic plasticity
LTP
ApoER2
ephrinB
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717312809

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http://www.sciencedirect.com/science/article/pii/S2211124717312809

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