Fission yeast Rad52 phosphorylation restrains error prone recombination pathways.

Rad52 is a key protein in homologous recombination (HR), a DNA repair pathway dedicated to double strand breaks and recovery of blocked or collapsed replication forks. Rad52 allows Rad51 loading on single strand DNA, an event required for strand invasion and D-loop formation. In addition, Rad52 func...

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Bibliographic Details
Main Authors: Angela Bellini, Pierre-Marie Girard, Ludovic Tessier, Evelyne Sage, Stefania Francesconi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3991707?pdf=render