Strong Replication Interference Between Hepatitis Delta Viruses in Human Liver Chimeric Mice

Strong Replication Interference Between Hepatitis Delta Viruses in Human Liver Chimeric Mice

BackgroundHepatitis D Virus (HDV) is classified into eight genotypes with distinct clinical outcomes. Despite the maintenance of highly conserved functional motifs, it is unknown whether sequence divergence between genotypes, such as HDV-1 and HDV-3, or viral interference mechanisms may affect co-in...

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Bibliographic Details
Main Authors: Katja Giersch, Lennart Hermanussen, Tassilo Volz, Annika Volmari, Lena Allweiss, Camille Sureau, John Casey, Jiabin Huang, Nicole Fischer, Marc Lütgehetmann, Maura Dandri
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Microbiology
Subjects:
HDV
genotypes
human liver chimeric mice
humanized mice
in vivo
replication
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.671466/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.671466/full

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