Differential O- and Glycosphingolipid Glycosylation in Human Pancreatic Adenocarcinoma Cells With Opposite Morphology and Metastatic Behavior

Differential O- and Glycosphingolipid Glycosylation in Human Pancreatic Adenocarcinoma Cells With Opposite Morphology and Metastatic Behavior

Changes in the glycosylation profile of cancer cells have been strongly associated with cancer progression. To increase our insights into the role of glycosylation in human pancreatic ductal adenocarcinoma (PDAC), we performed a study on O-glycans and glycosphingolipid (GSL) glycans of the PDAC cell...

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Bibliographic Details
Main Authors: Tao Zhang, Irma van Die, Boris Tefsen, Sandra J. van Vliet, Lisa C. Laan, Jing Zhang, Peter ten Dijke, Manfred Wuhrer, Ana I. Belo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Oncology
Subjects:
glycosylation
gene array analysis
glycosyltransferase
O-glycosylation
glycosphingolipid (GSL) glycans
pancreatic ductal adenocarcinoma
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00732/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.00732/full

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