Dynamics of Transcription Factor Binding Site Evolution.

Evolution of gene regulation is crucial for our understanding of the phenotypic differences between species, populations and individuals. Sequence-specific binding of transcription factors to the regulatory regions on the DNA is a key regulatory mechanism that determines gene expression and hence he...

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Bibliographic Details
Main Authors: Murat Tuğrul, Tiago Paixão, Nicholas H Barton, Gašper Tkačik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4636380?pdf=render