Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signallingResearch in context

Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signallingResearch in context

Background: Leukocyte-associated immunoglobulin like receptor-1 (LAIR1) is a transmembrane inhibitory receptor that influences susceptibility to a myriad of inflammatory diseases. Our recent investigations of severe malarial anaemia (SMA) pathogenesis in Kenyan children discovered that novel LAIR1 g...

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Bibliographic Details
Main Authors: Angela O. Achieng, Bernard Guyah, Qiuying Cheng, John M. Ong'echa, Collins Ouma, Christophe G. Lambert, Douglas J. Perkins
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419304219

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http://www.sciencedirect.com/science/article/pii/S2352396419304219

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