Impact of Adjuvant Chemotherapy on Survival of Patients with Advanced Residual Disease at Radical Cystectomy Following Neoadjuvant Chemotherapy: Systematic Review and Meta-Analysis

Impact of Adjuvant Chemotherapy on Survival of Patients with Advanced Residual Disease at Radical Cystectomy Following Neoadjuvant Chemotherapy: Systematic Review and Meta-Analysis

Background: Cisplatin-based neoadjuvant chemotherapy (NAC) followed by radical cystectomy (RC) with pelvic lymph-node dissection is the standard treatment for cT2-4a cN0 cM0 muscle-invasive bladder cancer (MIBC). Despite the significant improvement of primary-tumor downstaging with NAC, up to 50% of...

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Bibliographic Details
Main Authors: Wojciech Krajewski, Łukasz Nowak, Marco Moschini, Sławomir Poletajew, Joanna Chorbińska, Andrea Necchi, Francesco Montorsi, Alberto Briganti, Rafael Sanchez-Salas, Shahrokh F Shariat, Juan Palou, Marek Babjuk, Jeremy YC Teoh, Francesco Soria, Benjamin Pradere, Paola Irene Ornaghi, Aleksandra Pawlak, Janusz Dembowski, Romuald Zdrojowy
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Journal of Clinical Medicine
Subjects:
adjuvant chemotherapy
muscle-invasive bladder cancer
neoadjuvant chemotherapy
Online Access:https://www.mdpi.com/2077-0383/10/4/651

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https://www.mdpi.com/2077-0383/10/4/651

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