Evaluation of genotoxic effects of 3-methyl-5-(4-carboxycyclohexylmethyl)-tetrahydro-2H-1,3,5-thiadiazine-2-thione on human peripheral lymphocytes

Context: Tranexamic acid is commonly used for curing abnormal bleeding in a variety of diseases. In a previous study, 12 different tetrahydro-2H-1,3,5-thiadiazine derivatives were synthesized from the amine group of tranexamic acid. Their antifibrinolytic and antimicrobial activities were compared w...

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Bibliographic Details
Main Authors: Ece Avuloğlu-Yılmaz, Deniz Yüzbaşıoğlu, Azime Berna Özçelik, Seyhan Ersan, Fatma Ünal
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Pharmaceutical Biology
Subjects:
Online Access:http://dx.doi.org/10.1080/13880209.2017.1296000