The Cocktail Effect of BMP-2 and TGF-β1 Loaded in Visible Light-Cured Glycol Chitosan Hydrogels for the Enhancement of Bone Formation in a Rat Tibial Defect Model

The Cocktail Effect of BMP-2 and TGF-β1 Loaded in Visible Light-Cured Glycol Chitosan Hydrogels for the Enhancement of Bone Formation in a Rat Tibial Defect Model

Bone tissue engineering scaffolds offer the merits of minimal invasion as well as localized and controlled biomolecule release to targeted sites. In this study, we prepared injectable hydrogel systems based on visible light-cured glycol chitosan (GC) hydrogels containing bone morphogenetic protein-2...

Full description

Bibliographic Details
Main Authors: Sun-Jung Yoon, Youngbum Yoo, Sang Eun Nam, Hoon Hyun, Deok-Won Lee, Sewook Um, So Yeon Kim, Sung Ok Hong, Dae Hyeok Yang, Heung Jae Chun
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Marine Drugs
Subjects:
injectable hydrogel system
visible light-cured glycol chitosan
bone morphogenetic protein-2
transforming growth factor-beta1
bone formation
in vitro and in vivo
Online Access:http://www.mdpi.com/1660-3397/16/10/351

Internet

http://www.mdpi.com/1660-3397/16/10/351

Similar Items