CREB regulates TNF-α-induced GM-CSF secretion via p38 MAPK in human lung fibroblasts

CREB regulates TNF-α-induced GM-CSF secretion via p38 MAPK in human lung fibroblasts

Background: Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine that mediates eosinophilic differentiation, migration and survival, causing respiratory tract inflammation. GM-CSF is also known to be secreted from respiratory tract structural cells. However, the mechanisms of GM-C...

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Bibliographic Details
Main Authors: Yasuhiko Koga, Takeshi Hisada, Tamotsu Ishizuka, Mitsuyoshi Utsugi, Akihiro Ono, Masakiyo Yatomi, Yosuke Kamide, Haruka Aoki-Saito, Hiroaki Tsurumaki, Kunio Dobashi, Masanobu Yamada
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Allergology International
Subjects:
Asthma
cAMP
CREB
GM-CSF
p38 MAPK
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893016300284

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http://www.sciencedirect.com/science/article/pii/S1323893016300284

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