Chaperone-mediated autophagy: Advances from bench to bedside

Chaperone-mediated autophagy: Advances from bench to bedside

Protein homeostasis or proteostasis is critical for proper cellular function and survival. It relies on the balance between protein synthesis and degradation. Lysosomes play an important role in degrading and recycling intracellular components via autophagy. Among the three types of lysosome-based a...

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Bibliographic Details
Main Authors: Wenming Li, Tiejian Nie, Haidong Xu, Jing Yang, Qian Yang, Zixu Mao
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Neurobiology of Disease
Subjects:
Chaperone-mediated autophagy
Parkinson's disease
Neurodegenerative disease
Cancer
Therapy
ER stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118301487

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http://www.sciencedirect.com/science/article/pii/S0969996118301487

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