Loss of BAP1 expression is associated with genetic mutation and can predict outcomes in gallbladder cancer.

Loss of BAP1 expression is associated with genetic mutation and can predict outcomes in gallbladder cancer.

BACKGROUND:BRCA-1 associated protein (BAP1) is a de-ubiquitinating enzyme that regulates gene expression. Recently, the BAP1 mutation and its involvement in cancer survival have been reported in a range of tumor types, including uveal melanoma, mesothelioma, renal cancers, and biliary tract cancers....

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Bibliographic Details
Main Authors: Takashi Hirosawa, Masaharu Ishida, Kentaro Ishii, Keigo Kanehara, Katsuyoshi Kudo, Shinobu Ohnuma, Takashi Kamei, Fuyuhiko Motoi, Takeshi Naitoh, Florin M Selaru, Michiaki Unno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6218052?pdf=render

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http://europepmc.org/articles/PMC6218052?pdf=render

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