Local DNA methylation helps to regulate muscle sirtuin 1 gene expression across seasons and advancing age in gilthead sea bream (Sparus aurata)

Local DNA methylation helps to regulate muscle sirtuin 1 gene expression across seasons and advancing age in gilthead sea bream (Sparus aurata)

Abstract Background Sirtuins (SIRTs) are master regulators of metabolism, and their expression patterns in gilthead sea bream (GSB) reveal different tissue metabolic capabilities and changes in energy status. Since little is known about their transcriptional regulation, the aim of this work was to s...

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Bibliographic Details
Main Authors: Paula Simó-Mirabet, Erick Perera, Josep Alvar Calduch-Giner, Jaume Pérez-Sánchez
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Frontiers in Zoology
Subjects:
Fish
Sirtuins
DNA methylation
Epigenetic marks
Skeletal muscle
Age
Online Access:http://link.springer.com/article/10.1186/s12983-020-00361-1

Internet

http://link.springer.com/article/10.1186/s12983-020-00361-1

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