Non-clonal occurrence of pmrB mutations associated with polymyxin resistance in carbapenem-resistant Klebsiella pneumoniae in Brazil

Non-clonal occurrence of pmrB mutations associated with polymyxin resistance in carbapenem-resistant Klebsiella pneumoniae in Brazil

BACKGROUND Polymyxins are currently used as a “last-line” treatment for multidrug-resistant Gram-negative infections. OBJECTIVES To identify the major mechanisms of resistance to polymyxin and compare the genetic similarity between multi-drug resistant Klebsiella pneumoniae strains recovered from...

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Bibliographic Details
Main Authors: Ana Claudia Souza Rodrigues, Ivson Cassiano de Oliveira Santos, Caroline Conci Campos, Isadora Nascimento Rezende, Yanara Miranda Ferreira, Claudia Elisabeth Volpe Chaves, Cláudio Marcos Rocha-de-Souza, Ana Paula D’Alincourt Carvalho-Assef, Marilene Rodrigues Chang
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2019-05-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
colistin
polymyxins
multidrug resistance
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100328&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100328&lng=en&tlng=en

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