USP18 promotes cell proliferation and suppressed apoptosis in cervical cancer cells via activating AKT signaling pathway

USP18 promotes cell proliferation and suppressed apoptosis in cervical cancer cells via activating AKT signaling pathway

Abstract Background The deubiquitinating (DUB) enzyme ubiquitin-specific protease 18 (USP18), also known as UBP43, is an ubiquitin-specific protease linked to several human malignancies. However, USP18’s underlying function in human cervical cancer remains unclear. In the current study, we aimed to...

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Bibliographic Details
Main Authors: Wenjing Diao, Qisang Guo, Caiying Zhu, Yu Song, Hua Feng, Yuankui Cao, Ming Du, Huifen Chen
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Cancer
Subjects:
Cervical cancer
USP18
AKT
Proliferation
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12885-020-07241-1

Internet

http://link.springer.com/article/10.1186/s12885-020-07241-1

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