Liposome-Imipramine Blue Inhibits Sonic Hedgehog Medulloblastoma In Vivo

Liposome-Imipramine Blue Inhibits Sonic Hedgehog Medulloblastoma In Vivo

Sonic hedgehog subtype of medulloblastoma (SHH MB) with metastasis or specific clinical or molecular alteration shas a poor prognosis and current therapy results in long-term cognitive impairment in the majority of survivors. Thus, a great need exists for new targeted therapeutic approaches to more...

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Bibliographic Details
Main Authors: Tobey J. MacDonald, Jingbo Liu, Bing Yu, Anshu Malhotra, Jenny Munson, Jaekeun C. Park, Kenty Wang, Baowei Fei, Ravi Bellamkonda, Jack Arbiser
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
medulloblastoma
reactive oxygen
Nox4
sonic hedghog
Online Access:https://www.mdpi.com/2072-6694/13/6/1220

Internet

https://www.mdpi.com/2072-6694/13/6/1220

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