Hyperactivation of monocytes and macrophages in MCI patients contributes to the progression of Alzheimer's disease

Hyperactivation of monocytes and macrophages in MCI patients contributes to the progression of Alzheimer's disease

Abstract Background Alzheimer’s disease (AD) is the most common neurodegenerative disease ultimately manifesting as clinical dementia. Despite considerable effort and ample experimental data, the role of neuroinflammation related to systemic inflammation is still unsettled. While the implication of...

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Bibliographic Details
Main Authors: Usma Munawara, Michael Catanzaro, Weili Xu, Crystal Tan, Katsuiku Hirokawa, Nabil Bosco, David Dumoulin, Abdelouahed Khalil, Anis Larbi, Simon Lévesque, Charles Ramassamy, Annelise E. Barron, Stephen Cunnane, Pascale B. Beauregard, Jean-Pierre Bellenger, Serafim Rodrigues, Mathieu Desroches, Jacek M. Witkowski, Benoit Laurent, Eric H. Frost, Tamas Fulop
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Immunity & Ageing
Subjects:
Alzheimer’s disease
MCI neuroinflammation
monocytes
macrophages
phagocytosis
free radicals
Online Access:https://doi.org/10.1186/s12979-021-00236-x

Internet

https://doi.org/10.1186/s12979-021-00236-x

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