Carnitine insufficiency is associated with fatigue during lenvatinib treatment in patients with hepatocellular carcinoma.

BACKGROUND:Fatigue is a common adverse event during lenvatinib treatment in patients with hepatocellular carcinoma. One mechanism contributing to development of fatigue might involve abnormal adenosine triphosphate synthesis that is caused by carnitine deficiency. To address this possibility, we exa...

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Bibliographic Details
Main Authors: Hironao Okubo, Hitoshi Ando, Kei Ishizuka, Ryuta Kitagawa, Shoki Okubo, Hiroaki Saito, Shigehiro Kokubu, Akihisa Miyazaki, Kenichi Ikejima, Shuichiro Shiina, Akihito Nagahara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0229772