Use of a high resolution melting (HRM) assay to compare gag, pol, and env diversity in adults with different stages of HIV infection.

Use of a high resolution melting (HRM) assay to compare gag, pol, and env diversity in adults with different stages of HIV infection.

Cross-sectional assessment of HIV incidence relies on laboratory methods to discriminate between recent and non-recent HIV infection. Because HIV diversifies over time in infected individuals, HIV diversity may serve as a biomarker for assessing HIV incidence. We used a high resolution melting (HRM)...

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Bibliographic Details
Main Authors: Matthew M Cousins, Oliver Laeyendecker, Geetha Beauchamp, Ronald Brookmeyer, William I Towler, Sarah E Hudelson, Leila Khaki, Beryl Koblin, Margaret Chesney, Richard D Moore, Gabor D Kelen, Thomas Coates, Connie Celum, Susan P Buchbinder, George R Seage, Thomas C Quinn, Deborah Donnell, Susan H Eshleman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3206918?pdf=render

Internet

http://europepmc.org/articles/PMC3206918?pdf=render

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