Effect of β-Blocker in Treatment-Naïve Patients With Advanced Lung Adenocarcinoma Receiving First-Generation EGFR-TKIs

Effect of β-Blocker in Treatment-Naïve Patients With Advanced Lung Adenocarcinoma Receiving First-Generation EGFR-TKIs

BackgroundThrough activation of adrenergic receptors, chronic stress can trigger the secretion of neurotransmitters and hormones that enhance tumor growth, increase angiogenesis, and promote drug resistance. This study aimed to evaluate the effect of β-blockers in patients receiving first-line epide...

Full description

Bibliographic Details
Main Authors: Chia-Hao Chang, Chih-Hsin Lee, Jen-Chung Ko, Lih-Yu Chang, Ming-Chia Lee, Jun-Fu Zhang, Jann-Yuan Wang, Jin-Yuan Shih, Chong-Jen Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
lung cancer
epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI)
β-blocker
overall survival
time-to-discontinuation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.583529/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.583529/full

Similar Items