LncEGFL7OS regulates human angiogenesis by interacting with MAX at the EGFL7/miR-126 locus

LncEGFL7OS regulates human angiogenesis by interacting with MAX at the EGFL7/miR-126 locus

In an effort to identify human endothelial cell (EC)-enriched lncRNAs,~500 lncRNAs were shown to be highly restricted in primary human ECs. Among them, lncEGFL7OS, located in the opposite strand of the EGFL7/miR-126 gene, is regulated by ETS factors through a bidirectional promoter in ECs. It is enr...

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Bibliographic Details
Main Authors: Qinbo Zhou, Bo Yu, Chastain Anderson, Zhan-Peng Huang, Jakub Hanus, Wensheng Zhang, Yu Han, Partha S Bhattacharjee, Sathish Srinivasan, Kun Zhang, Da-zhi Wang, Shusheng Wang
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-02-01
Series:eLife
Subjects:
lncRNA
angiogenesis
endothelial cell
miR-126
Online Access:https://elifesciences.org/articles/40470

Internet

https://elifesciences.org/articles/40470

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