Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants.

Glial innate immunity generated by non-aggregated alpha-synuclein in mouse: differences between wild-type and Parkinson's disease-linked mutants.

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized pathologically by the presence in the brain of intracellular protein inclusions highly enriched in aggregated alpha-synuclein (α-Syn). Although it has been established that progression of the disease is accompani...

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Main Authors: Cintia Roodveldt, Adahir Labrador-Garrido, Elena Gonzalez-Rey, Rafael Fernandez-Montesinos, Marta Caro, Christian C Lachaud, Christopher A Waudby, Mario Delgado, Christopher M Dobson, David Pozo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2964342?pdf=render

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http://europepmc.org/articles/PMC2964342?pdf=render

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