Natural polymorphisms in Tap2 influence negative selection and CD4∶CD8 lineage commitment in the rat.
Genetic variation in the major histocompatibility complex (MHC) affects CD4∶CD8 lineage commitment and MHC expression. However, the contribution of specific genes in this gene-dense region has not yet been resolved. Nor has it been established whether the same genes regulate MHC expression and T cel...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-02-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3930506?pdf=render |