The Role of NRF2/KEAP1 Signaling Pathway in Cancer Metabolism
The nuclear factor-erythroid 2 p45-related factor 2 (NRF2, also called <i>Nfe2l2</i>) and its cytoplasmic repressor, Kelch-like ECH-associated protein 1 (KEAP1), are major regulators of redox homeostasis controlling a multiple of genes for detoxification and cytoprotective enzymes. The N...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-04-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/22/9/4376 |