Induction Murine Models of Chronic Fatigue Syndrome by Brucella abortus Antigen Injections: Is Anemia Induced or Not?

To investigate whether Brucella abortus (BA) antigen injections lead to anemia, and to establish an appropriate Chronic Fatigue Syndrome (CFS) animal model by BA injections, 6 repeated injections of BA antigen were fulfilled every 2 weeks. At a high dose of 1∗1010 particles/mouse, anemia was induced...

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Bibliographic Details
Main Authors: Junji Moriya, Qiang He, Hiroaki Uenishi, Sumiyo Akazawa, Jun-ichi Yamakawa, Junji Kobayashi, Yasuhito Ishigaki
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/191489