Therapeutic efficacy of intra-articular hyaluronan derivative and platelet-rich plasma in mice following axial tibial loading.

Therapeutic efficacy of intra-articular hyaluronan derivative and platelet-rich plasma in mice following axial tibial loading.

OBJECTIVE:To investigate the therapeutic potential of intra-articular hyaluronan-derivative HYADD® 4-G and/or platelet-rich plasma (PRP) in a mouse model of non-invasive joint injury. METHODS:Non-invasive axial tibial loading was used to induce joint injury in 10-week-old C57BL/6J mice (n = 86). Mic...

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Bibliographic Details
Main Authors: Xin Duan, Linda J Sandell, Nobuaki Chinzei, Nilsson Holguin, Matthew J Silva, Antonella Schiavinato, Muhammad Farooq Rai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5391072?pdf=render

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http://europepmc.org/articles/PMC5391072?pdf=render

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