The history of mianserin and mirtazapine: study of their neurochemical activity and determination of their position in the classification of antidepressants

The history of mianserin and mirtazapine: study of their neurochemical activity and determination of their position in the classification of antidepressants

The paper systematizes the history of studying the neurochemical activity of mianserin and mirtazapine. The concept of the development of the antidepressant effect of these drugs, by stimulating the release of norepinephrine into the synaptic cleft, is shown to have gained unanimously acceptance. Th...

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Bibliographic Details
Main Authors: D. S. Danilov, Yu. G. Tyulpin, V. D. Morozova
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2020-04-01
Series:Nevrologiâ, Nejropsihiatriâ, Psihosomatika
Subjects:
mianserin
mirtazapine
α2-adrenergic receptors
serotonin 5-ht2 receptors
norepinephrine
serotonin
α2-adrenergic receptor blockers
noradrenalinergic and specific serotonergic antidepressants
norepinephrine and serotonin release stimulators – α2-adrenergic and serotonin 5-ht2 receptor blockers
history of antidepressants
Online Access:https://nnp.ima-press.net/nnp/article/view/1313

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https://nnp.ima-press.net/nnp/article/view/1313

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