Silencing of lncRNA UCA1 inhibited the pathological progression in PCOS mice through the regulation of PI3K/AKT signaling pathway

Silencing of lncRNA UCA1 inhibited the pathological progression in PCOS mice through the regulation of PI3K/AKT signaling pathway

Abstract Background Polycystic ovary syndrome (PCOS) is the most common hormonal disorder among reproductive-aged women worldwide, however, the mechanisms and progression of PCOS still unclear due to its heterogeneous nature. Using the human granulosa-like tumor cell line (KGN) and PCOS mice model,...

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Bibliographic Details
Main Authors: Dongyong Yang, Yanqing Wang, Yajing Zheng, Fangfang Dai, Shiyi Liu, Mengqin Yuan, Zhimin Deng, Anyu Bao, Yanxiang Cheng
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Ovarian Research
Subjects:
UCA1
PCOS
Inflammation
lncRNA
Granulosa cell
Online Access:https://doi.org/10.1186/s13048-021-00792-2

Internet

https://doi.org/10.1186/s13048-021-00792-2

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