Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa

Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa

Abstract Background Traumatic brain injury (TBI) is a devastating neurological condition and a frequent cause of permanent disability. Posttraumatic inflammation and brain edema formation, two pathological key events contributing to secondary brain injury, are mediated by the contact-kinin system. A...

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Bibliographic Details
Main Authors: Sarah Hopp, Marc W. Nolte, Christian Stetter, Christoph Kleinschnitz, Anna-Leena Sirén, Christiane Albert-Weissenberger
Format: Article
Language:English
Published: BMC 2017-02-01
Series:Journal of Neuroinflammation
Subjects:
Focal brain lesion
Brain edema
Factor XII
Online Access:http://link.springer.com/article/10.1186/s12974-017-0815-8

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http://link.springer.com/article/10.1186/s12974-017-0815-8

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