Shwachman-Bodian-Diamond syndrome protein desensitizes breast cancer cells to apoptosis in stiff matrices by repressing the caspase 8-mediated pathway

Shwachman-Bodian-Diamond syndrome protein desensitizes breast cancer cells to apoptosis in stiff matrices by repressing the caspase 8-mediated pathway

Certain cancer types, including breast cancer, are accompanied with stiffening of the surrounding extracellular matrix (ECM). Previous studies suggest that this stiffened matrix influences cancer cell progression, such as proliferation and invasion, both biochemically and mechanically. However, the...

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Bibliographic Details
Main Authors: Jieun Lee, Panseon Ko, Eunae You, Jangho Jeong, Seula Keum, Jaegu Kim, Mizanur Rahman, Dong Ho Lee, Sangmyung Rhee
Format: Article
Language:English
Published: Taylor & Francis Group 2019-11-01
Series:Animal Cells and Systems
Subjects:
sbds
breast cancer
ecm stiffness
apoptosis
caspase
Online Access:http://dx.doi.org/10.1080/19768354.2019.1666030

Internet

http://dx.doi.org/10.1080/19768354.2019.1666030

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