Unique divergence of the breast cancer 2 (BRCA2) gene in Neanderthals

Abstract Unique divergence of the BRCA2, a tumor suppressor gene, in Neanderthals relative to other primates, including modern humans, is highlighted. This divergence with potentially pathogenic consequences raises a question about cancer susceptibility in the archaic species that was replaced by mo...

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Bibliographic Details
Main Authors: Pawel Michalak, Lin Kang
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Hereditas
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41065-018-0073-5