Defining early human NK cell developmental stages in primary and secondary lymphoid tissues.

A better understanding of human NK cell development in vivo is crucial to exploit NK cells for immunotherapy. Here, we identified seven distinctive NK cell developmental stages in bone marrow of single donors using 10-color flow cytometry and found that NK cell development is accompanied by early ex...

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Bibliographic Details
Main Authors: Diana N Eissens, Jan Spanholtz, Arnold van der Meer, Bram van Cranenbroek, Harry Dolstra, Jaap Kwekkeboom, Frank W M B Preijers, Irma Joosten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3272048?pdf=render