Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemia

Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemia

We conducted a genome-wide scan using variance components linkage analysis to localize quantitative-trait loci (QTLs) influencing triglyceride (TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol, and total cholesterol (TC) levels in 3,071 subjects from 459 familie...

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Bibliographic Details
Main Authors: Yi Yu, Diego F. Wyszynski, Dawn M. Waterworth, Steven D. Wilton, Philip J. Barter, Y. Antero Kesäniemi, Robert W. Mahley, Ruth McPherson, Gérard Waeber, Thomas P. Bersot, Qianli Ma, Sanjay S. Sharma, Douglas S. Montgomery, Lefkos T. Middleton, Scott S. Sundseth, Vincent Mooser, Scott M. Grundy, Lindsay A. Farrer
Format: Article
Language:English
Published: Elsevier 2005-10-01
Series:Journal of Lipid Research
Subjects:
cardiovascular disease
epistatic effects
genetic linkage analysis
metabolic syndrome
variance components analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520329114

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http://www.sciencedirect.com/science/article/pii/S0022227520329114

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