A novel fluorogenic substrate for the measurement of endothelial lipase activity

Endothelial lipase (EL) is a phospholipase A1 (PLA1) enzyme that hydrolyzes phospholipids at the sn-1 position to produce lysophospholipids and free fatty acids. Measurement of the PLA1 activity of EL is usually accomplished by the use of substrates that are also hydrolyzed by lipases in other subfa...

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Bibliographic Details
Main Authors: Andrew L. Darrow, Matthew W. Olson, Hong Xin, Sharon L. Burke, Charles Smith, Celine Schalk-Hihi, Robyn Williams, Shariff S. Bayoumy, Ingrid C. Deckman, Matthew J. Todd, Bruce P. Damiano, Margery A. Connelly
Format: Article
Language:English
Published: Elsevier 2011-02-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520405334