Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.

Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.

The NADPH oxidase 2 (NOX2) complex is a professional producer of reactive oxygen species (ROS) and is mainly expressed in phagocytes. While the activity of the NOX2 complex is essential for immunity against pathogens and protection against autoimmunity, its role in the development of malignant tumor...

Full description

Bibliographic Details
Main Authors: Tiina Kelkka, Angela Pizzolla, Juha Petteri Laurila, Tomas Friman, Renata Gustafsson, Eva Källberg, Olof Olsson, Tomas Leanderson, Kristofer Rubin, Marko Salmi, Sirpa Jalkanen, Rikard Holmdahl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3865299?pdf=render

Internet

http://europepmc.org/articles/PMC3865299?pdf=render

Similar Items