Neighborhood Regularized Logistic Matrix Factorization for Drug-Target Interaction Prediction.

In pharmaceutical sciences, a crucial step of the drug discovery process is the identification of drug-target interactions. However, only a small portion of the drug-target interactions have been experimentally validated, as the experimental validation is laborious and costly. To improve the drug di...

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Bibliographic Details
Main Authors: Yong Liu, Min Wu, Chunyan Miao, Peilin Zhao, Xiao-Li Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4752318?pdf=render