Untargeted metabolomics and transcriptomics identified glutathione metabolism disturbance and PCS and TMAO as potential biomarkers for ER stress in lung

Untargeted metabolomics and transcriptomics identified glutathione metabolism disturbance and PCS and TMAO as potential biomarkers for ER stress in lung

Abstract Endoplasmic reticulum (ER) stress is a cellular state that results from the overload of unfolded/misfolded protein in the ER that, if not resolved properly, can lead to cell death. Both acute lung infections and chronic lung diseases have been found related to ER stress. Yet no study has be...

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Bibliographic Details
Main Authors: Zijing Wang, Peng Ma, Yisa Wang, Biyu Hou, Can Zhou, He Tian, Bowen Li, Guanghou Shui, Xiuying Yang, Guifen Qiang, Chengqian Yin, Guanhua Du
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92779-8

Internet

https://doi.org/10.1038/s41598-021-92779-8

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