SIRT1 Inhibition Affects Angiogenic Properties of Human MSCs

Human mesenchymal stem cells (hMSCs) are attractive for clinical and experimental purposes due to their capability of self-renewal and of differentiating into several cell types. Autologous hMSCs transplantation has been proven to induce therapeutic angiogenesis in ischemic disorders. However, the m...

Full description

Bibliographic Details
Main Authors: Botti Chiara, Caiafa Ilaria, Coppola Antonietta, Cuomo Francesca, Miceli Marco, Altucci Lucia, Cobellis Gilda
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/783459