LATS2 promotes apoptosis in non-small cell lung cancer A549 cells via triggering Mff-dependent mitochondrial fission and activating the JNK signaling pathway

LATS2 is a classical tumor suppressor that affects non-small cell lung cancer proliferation and mobilization. However, its role in lung cancer cell apoptosis is unknown. The aim of our study is to explore whether LATS2 activates mitochondria-related apoptosis in lung cancer cells. In the present stu...

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Bibliographic Details
Main Authors: Yudong Xie, Yanping Lv, Yanli Zhang, Zhenzhen Liang, Lili Han, Yiyang Xie
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218370835