Effects of anti-angiogenesis on glioblastoma growth and migration: model to clinical predictions.

Glioblastoma multiforme (GBM) causes significant neurological morbidity and short survival times. Brain invasion by GBM is associated with poor prognosis. Recent clinical trials of bevacizumab in newly-diagnosed GBM found no beneficial effects on overall survival times; however, the baseline health-...

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Bibliographic Details
Main Authors: Elizabeth Scribner, Olivier Saut, Paula Province, Asim Bag, Thierry Colin, Hassan M Fathallah-Shaykh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4266618?pdf=render