The Helicase PIF1 Facilitates Resection over Sequences Prone to Forming G4 Structures

Summary: DNA breaks are complex lesions that can be repaired either by non-homologous end joining (NHEJ) or by homologous recombination (HR). The decision between these two routes of DNA repair is a key point of the DNA damage response (DDR) that is controlled by DNA resection. The core machinery ca...

Full description

Bibliographic Details
Main Authors: Sonia Jimeno, Rosa Camarillo, Fernando Mejías-Navarro, Maria Jesús Fernández-Ávila, Isabel Soria-Bretones, Rosario Prados-Carvajal, Pablo Huertas
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718313330