Strain-Dependent Inhibition of Erythrocyte Invasion by Monoclonal Antibodies Against Plasmodium falciparum CyRPA

Strain-Dependent Inhibition of Erythrocyte Invasion by Monoclonal Antibodies Against Plasmodium falciparum CyRPA

The highly conserved Plasmodium falciparum cysteine-rich protective antigen (PfCyRPA) is a key target for next-generation vaccines against blood-stage malaria. PfCyRPA constitute the core of a ternary complex, including the reticulocyte binding-like homologous protein 5 (PfRh5) and the Rh5-interacti...

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Bibliographic Details
Main Authors: Anne S. Knudsen, Kasper H. Björnsson, Maria R. Bassi, Melanie R. Walker, Andreas Kok, Bogdan Cristinoi, Anja R. Jensen, Lea Barfod
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
Plasmodium falciparum
merozoite
PfCyRPA
inhibition
synergy
strain-dependence
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.716305/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.716305/full

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