Oncogenic BRAF Alterations and Their Role in Brain Tumors
Alterations of the v-raf murine sarcoma viral oncogene homolog B (BRAF) have been extensively studied in several tumor entities and are known to drive cell growth in several tumor entities. Effective targeted therapies with mutation-specific small molecule inhibitors have been developed and establis...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-06-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/11/6/794 |