Zebrafish models for ectopic mineralization disorders: practical issues from morpholino design to post-injection observations

Zebrafish (ZF, Danio rerio) has emerged as an important and popular model species to study different human diseases. Key regulators of skeletal development and calcium metabolism are highly conserved between mammals and zebrafish. The corresponding orthologs share significant sequence similarities a...

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Bibliographic Details
Main Authors: Mohammad Jakir Hosen, Olivier M. Vanakker, Andy eWillaert, Ann eHuysseune, Paul eCoucke, Anne eDe Paepe
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00074/full