JC Polyomavirus (JCV) and Monoclonal Antibodies: Friends or Potential Foes?

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system (CNS), observed in immunodeficient patients and caused by JC virus ((JCV), also called JC polyomavirus (JCPyV)). After the HIV pandemic and the introduction of immunomodulatory therapy, the PML...

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Bibliographic Details
Main Authors: Roberta Antonia Diotti, Akira Nakanishi, Nicola Clementi, Nicasio Mancini, Elena Criscuolo, Laura Solforosi, Massimo Clementi
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2013/967581