Modeling Human Cytomegalovirus in Humanized Mice for Vaccine Testing

Human cytomegalovirus (HCMV or HHV-5) is a globally spread pathogen with strictly human tropism that establishes a lifelong persistence. After primary infection, high levels of long-term T and B cell responses are elicited, but the virus is not cleared. HCMV persists mainly in hematopoietic reservoi...

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Bibliographic Details
Main Authors: Johannes Koenig, Sebastian J. Theobald, Renata Stripecke
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Vaccines
Subjects:
cmv
his
Online Access:https://www.mdpi.com/2076-393X/8/1/89