Tumor SQSTM1 (p62) expression and T cells in colorectal cancer

Tumor SQSTM1 (p62) expression and T cells in colorectal cancer

Evidence suggests that activation of autophagy in neoplastic cells potentiates antitumor immunity through cross-presentation of tumor-associated antigens to T cells and release of immune mediators. The SQSTM1 (sequestosome 1, p62) protein is degraded by activated autophagy, and might enhance immune...

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Bibliographic Details
Main Authors: Keisuke Kosumi, Yohei Masugi, Juhong Yang, Zhi Rong Qian, Sun A. Kim, Wanwan Li, Yan Shi, Annacarolina da Silva, Tsuyoshi Hamada, Li Liu, Mancang Gu, Tyler S. Twombly, Yin Cao, David A. Barbie, Katsuhiko Nosho, Hideo Baba, Wendy S. Garrett, Jeffery A. Meyerhardt, Edward L. Giovannucci, Andrew T. Chan, Charles S. Fuchs, Shuji Ogino, Reiko Nishihara
Format: Article
Language:English
Published: Taylor & Francis Group 2017-03-01
Series:OncoImmunology
Subjects:
adenocarcinoma
colorectum
immunoprevention
immunotherapy
molecular pathology
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1284720

Internet

http://dx.doi.org/10.1080/2162402X.2017.1284720

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